The Application of a Highly Purified Rat Leydig Cell Assay as a Complement to the H295R Steroidogenesis Assay for the Evaluation of Toxicant Induced Alterations in Testosterone Production

The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not detected by the high throughput screening format of the H295R steroidogenesis assay. This dataset is associated with the following publication: Klinefelter , G., J. Laskey, and R. Amann. Statin Drugs Markedly Inhibit Testosterone Production by Rat Leydig Cells In Vitro: Implications for Men. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, USA, 45: 52-58, (2014). NOTE: This dataset has been removed from public access due to revocation. Please refer inquiries regarding this dataset to the listed contact person.

Data and Resources

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Additional Info

Field	Value
Maintainer	Gary Klinefelter
Last Updated	March 17, 2021, 00:41 (EDT)
Created	March 17, 2021, 00:41 (EDT)
Identifier	https://doi.org/10.23719/1367522
Modified	2017-06-16
accessLevel	public
bureauCode	{020:00}
catalog_conformsTo	https://project-open-data.cio.gov/v1.1/schema
encoding	utf8
harvest_url	http://catalog.data.gov/dataset/32cbc53e-6c06-4276-a597-4de95f5e7f9a
license	https://pasteur.epa.gov/license/sciencehub-license.html
programCode	{020:000}
publisher	U.S. EPA Office of Research and Development (ORD)
publisher_hierarchy	U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
resource-type	Dataset
source_datajson_identifier	true
source_hash	0820c0d1378308c657158bf4f3cc1476c68499e3
source_schema_version	1.1