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formalin effects data

RNA sequencing data from paired: (1) fresh-frozen, (2) direct-fixed in formalin for 18 hours, (3) frozen then formalin-fixed, or (4) frozen then ethanol-fixed and paraffin-embedded (n=6/group/condition) tissue samples from the livers of mice exposed to 600 ppm phenobarbital vs. vehicle control for 7 days in drinking water. RNA sequencing data from paired fresh frozen and 18 hr. formalin-fixed paraffin-embedded liver tissue from mice administered 1500, 3000, and 6000 ppm DEHP or vehicle control for 7 days by dietary ingestion; or RNA sequencing data from paired fresh frozen, 18 hr. formalin fixed paraffin embedded, or 3 wk. formalin fixed paraffin embedded liver tissue from mice administered 8 mg/kg/d Furan or vehicle control for 3 weeks by gavage.

This dataset is associated with the following publication: Wehmas, L., S. Hester, and C.E. Wood. Direct Formalin Fixation Induces Widespread Transcriptomic Effects in Archival Tissue Samples. Scientific Reports. Nature Publishing Group, London, UK, 10: 14497, (2020).

Data and Resources

Additional Info

Field Value
Maintainer Leah Wehmas
Last Updated March 7, 2021, 22:50 (EST)
Created March 7, 2021, 22:50 (EST)
Identifier https://doi.org/10.23719/1518503
Modified 2020-04-21
accessLevel public
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harvest_url http://catalog.data.gov/dataset/2e206412-c432-466a-b75c-62d2b000a93b
license https://pasteur.epa.gov/license/sciencehub-license.html
programCode {020:095}
publisher U.S. EPA Office of Research and Development (ORD)
publisher_hierarchy U.S. Government > U.S. Environmental Protection Agency > U.S. EPA Office of Research and Development (ORD)
references {https://doi.org/10.1038/s41598-020-71521-w}
resource-type Dataset
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source_hash 501347efac97a6af8f5ab2aa3170545ca4198d70
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