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From the dataset abstract

This dataset represents the estimated density of georeferenced sites within individual local and accumulated upstream catchments for NHDPlusV2 Waterbodies based on the EPA's Facility...

Source: The LakeCat Dataset: Accumulated Attributes for NHDPlusV2 (Version 2.1) lake catchments and watersheds for the Conterminous United States: Facility Registry Services (FRS) : Toxic Release Inventory (TRI) , National Pollutant Discharge Elimination System (NPDES) , and Superfund Sites